nervous 4 antonyms and opposites of nervous. Adj — Easily agitated, anxious, or worried, especially about an upcoming event. Synonyms for nervous angstful apprehensive anxious careful concerned distraught disturbed edgy fraught freaked out hagridden high-strung jittery jumpy nervy leery on edge perturbable skittish restless spookish squeamish tied in knots twitchy uneasy unquiet verklempt worrisome worried worryful Antonyms for nervous calm intrepid unperturbed unworried ← Back to the full definition of nervous